Domesticated animals such as dogs, cats, cattle, sheep, goats, pigs, horses, and poultry, as well as wildlife are big challenges to on-farm food safety, both in the field and packing shed. However, handling and monitoring domesticated animals is comparatively easier than wildlife (which is covered in the Wildlife Management factsheet). Although domesticated animals are often used in fields as draft animals, for wildlife management, and to graze on crop residues/culls, the fecal matter left behind in the field can be a significant source of human pathogens, including E. coli O157:H7, Listeria, Salmonella, and Cryptosporidium. Droppings from poultry, wild birds, and even pets are a potential source of pathogens as well. The pathogen load carried by domesticated animals is influenced by a number of factors such as age of animals, type of animal, rearing practices, and other factors. Domesticated animals, if not limited to secured areas on the farm, can cause cross-contamination and result in food borne disease outbreaks.